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In addition to Sodium, your body needs potassium, calcium, magnesium and phosphate all of which are electrolytes

This Ca 2+ effect of the thiazides is an indirect consequence of their inhibition of the apical membrane-associated NCC transporter

6 Conclusion A growing body of experimental and clinical data highlights the important role of the RAS in the pathophysiology of mood disorders

doi: 10.1016/j.bbapap.2017.07.003 46